关键词: 老鹳草, 微胶囊, 复合织物, 涂层, 缓释

Abstract:

In order to control the release speed of the drug in the compound fabric and prolong its release process, the Geranium wilfordii Maxim (GWM) extracts were encapsulated into polyvinyl alcohol (PVA) by interfacial polymerization. The GWM microcapsules were coated on cotton knits using water-borne polyurethane (PU)adhesive by direct coating. The morphology, particle size, thermal stabilityand slow-release properties of the microcapsules and the morphology and slow-release properties of the composite fabric were studied using SEM, TG and ultraviolet-visible (UV-VIS) spectrophotometer. The results indicates that the surface of GWM/PVA microcapsules is smooth, and the average particle size is 23.9 μm. The GWM/PVA microcapsules with a drug loading ratio of 33.0% show good thermal stability at 325°C. The release process following the non-fickian diffusion mechanism can last for more than 24 h in the buffer solution. The release process of the composite  fabric the similar diffusion mechanism. The release time is prolonged in the buffer solution.

Key words: Geranium wilfordii Maxim, microcapsule, compound fabric, coating, slow-release