Journal of Textile Research ›› 2019, Vol. 40 ›› Issue (12): 140-145.doi: 10.13475/j.fzxb.20181206406

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Research progress of electrospun animal protein nanofibers

LÜ Tingting, AN Ying, LI Haoyi(), LIU Yujian, JIAO Zhiwei   

  1. College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
  • Received:2018-12-29 Revised:2019-08-25 Online:2019-12-15 Published:2019-12-18
  • Contact: LI Haoyi E-mail:lhy@mail.buct.edu.cn

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Abstract:

In order to expand the application field of electrospinning nanofibers and broaden the material sources of electrospinning process, the recent research progress of electrospinning animal protein nanofibers at home and abroad was reviewed. In view of the denaturation of protein by organic solvents in current electrospinning process, several methods of substituting organic solvents were introduced, and their advantages and disadvantages were compared. It was concluded that water-soluble polymers were more advantageous than organic solvents in the application of protein nanofibers in the field of biomedicine. The influences of cross-linking modification and blending modification on the mechanical properties of electrospun animal protein nanofibers were discussed. The application of electrospun collagen nanofibers in biomedical field was summarized. Finally, the urgent problems and future development directions of electrospun animal protein nanofibers were prospected.

Key words: electrospinning, animal protein, nanofiber, solvent, collagen protein

CLC Number: 

  • TH16

Fig.1

Schematic diagram of electrospinning device"

Fig.2

Schematic diagram of coaxial electrospinning"

Tab.1

Comparison of solvent selection in electrospinning"

溶剂的选择 优点 缺点 参考文献
无毒性、环境友好型溶剂 无毒性,生物可降解性 不能保护蛋白质的活性 [16-17]
离子液体 45 ℃时胶原蛋白溶解度提升至11% 离子液价格昂贵,成本增加 [19]
同轴静电纺隔离溶剂 隔离了蛋白质与有机溶剂 装置结构复杂 [22]
水溶性聚合物与蛋白共混 以水作为溶剂,无有毒溶剂的残留 溶液浓度配比要求较高 [23]

Tab.2

Major sources of animal collagen"

动物胶原蛋白主要来源 胶原蛋白类型
牛皮 Ⅰ型、Ⅲ型
鸡肋软骨 Ⅱ型
鼠尾腱 Ⅰ型
山羊皮 Ⅰ型、Ⅲ型
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