纺织学报 ›› 2019, Vol. 40 ›› Issue (05): 102-106.doi: 10.13475/j.fzxb.20180500905

• 染整与化学品 • 上一篇    下一篇

可溶性止血医用棉纱布的制备及其性能

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  • 收稿日期:2018-05-02 修回日期:2019-01-02 出版日期:2019-05-15 发布日期:2019-05-21

Preparation and characterization of soluble hemostatic medical cotton gauze

  • Received:2018-05-02 Revised:2019-01-02 Online:2019-05-15 Published:2019-05-21

摘要:

为提高羧甲基化医用棉纱布的可溶性,发挥其止血作用,采用单因素法探究溶媒法制备工艺。考察了碱化预处理的碱液质量分数、碱化时间和醚化反应的氯乙酸质量分数、醚化时间和醚化温度等因素对棉纱布溶解性能的影响,确定出较佳制备工艺,并借助红外光谱仪、扫描电子显微镜对所制得的可溶性止血纱布进行表征。结果表明:在较佳的可溶性止血纱布制备工艺下,即碱化预处理时碱液质量分数为20%、碱化时间为30 min,醚化时氯乙酸质量分数为10. 5%、醚化时间为4 h、醚化温度为70 ℃,棉纱布完全溶解所需时间为4 h;棉纱布发生了羧甲基化反应,羧甲基化后纤维直径增加。

关键词: 医用纱布, 羧甲基化, 溶媒法, 溶解性能

Abstract:

In order to improve the solubility of carboxymethyl medical cotton gauze to achieve good hemostatic effect, single factor analytical method was adopted to investigate the process conditions of solvent medium method. The influence of the mass fraction of sodium hydroxide and time of alkalization pre-treatment, the mass fraction of chloroacetic acid, temperature and time of etherification reaction on the solubility of cotton gauze were studied. The optimum preparation processes were obtained and the soluble hemostatic gauzes were characterized by Fourier transform infrared spectrometer and scanning electronic microscopy. The results show that the optimum soluble hemostatic gauzes are produced under the condition of 20% mass fraction of sodium hydroxide and alkalization pre-treatment for 30 min, 10. 5% mass fraction of chloroacetic acid, etherification at 70 ℃ for 4 h, while the dissolution time is 4 h. The cotton gauze is carboxymethylated, and the diameters of fibers increase after carboxymethylation.

Key words: medical gauze, carboxymethylation, solvent medium method, solubility

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