Abstract: Iron-tetrasulfophthalocyanine as homogeneous photocatalyst was difficult to separate and couldn′t be reused. A supported catalyst was obtained by reaction between modified cotton fibers and iron-tetrasulfophthalocyanine. Upon visible light irradiation in the presence of H2O2, this catalyst was found to be highly effective for the degradation of nonbiodegradable active red. The effects of dosage of catalyst, pH value and lamp-house on the catalytic oxdition were investigated. The experiments indicated that active red in aqueous solution was decolored near 100% with COD removal rate of 67%, when the fiber dosage 1.0g/L, the H2O2 dosage 0.19mol/L, pH=4.93, irradiated by simulant visible light . The catalyst was recyclable and it wound not cause any secondary pollution.