Abstract: Silk sericin was used as material to prepare sericin film varying drying temperatures.The effect of drying temperature on the structure of sericin film was researched by using X-ray diffraction,infrared spectroscopy,and DTA.The results showed that drying temperature had obviously influence on aggregation structure of sericin protein in temperature range of 30-(100 ℃.) The aggregation structure dried at(30 ℃) was mostly amorphous.With the temperature increasing,the tightness of sericin protein′s aggregation structure was increased and,became obvious above(80 ℃.)The important temperature point for significant modification of sericin protein structure was about(40 ℃.)