Abstract: The mesoporous SBA-15 was modified with 3-aminopropyl-triethoxysilane via post-synthesis silylation methods. Then the AgNO3 solution was dipped into the modified SBA-15 powder and the antibacterial composites were synthesized. Through XRD,FTIR,EDS,FESEM and TG, these composites were characterized. The experimental results reveal that the amino functional groups were grafted on the mesoporous SBA-15 and the Ag nanoparticles existed in the pore channels of SBA-15.