纺织学报 ›› 2020, Vol. 41 ›› Issue (11): 66-72.doi: 10.13475/j.fzxb.20191100307

• 纺织工程 • 上一篇    下一篇

典型纺织基人工韧带及其移出物结构与力学性能

刘明洁1,2, 林婧1,2, 关国平1,2(), BROCHU G3, GUIDOIN R3, 王璐1,2   

  1. 1.东华大学 纺织学院, 上海 201620
    2.东华大学 纺织面料技术教育部重点实验室, 上海 201620
    3.拉法尔大学 外科系, 魁北克 G1V0A6, 加拿大
  • 收稿日期:2019-11-01 修回日期:2020-05-15 出版日期:2020-11-15 发布日期:2020-11-26
  • 通讯作者: 关国平
  • 作者简介:刘明洁(1996—),女,硕士生。主要研究方向为生物医用纺织材料。
  • 基金资助:
    国家重点研发计划项目(2018YFC1106200)

Structures and mechanical properties of typical textile-based artificial ligaments and explants

LIU Mingjie1,2, LIN Jing1,2, GUAN Guoping1,2(), BROCHU G3, GUIDION R3, WANG Lu1,2   

  1. 1. College of Textiles, Donghua University, Shanghai 201620, China
    2. Key Laboratory of Textiles Scienceand Technology, Ministry of Education, Donghua University, Shanghai 201620, China
    3. Department of Surgery, Laval University, Quebec G1V0A6, Canada
  • Received:2019-11-01 Revised:2020-05-15 Online:2020-11-15 Published:2020-11-26
  • Contact: GUAN Guoping

摘要:

针对目前临床上人工韧带产品需求量大但淘汰率高的问题,从几何特征、织造方式、表面形态等方面对当前11种典型纺织基人工韧带进行了系统分析,同时对比分析了典型产品Stryker?-Meadox的移出样和原样的力学性能、纤维形貌、降解性能等,并对其体内失效机制进行了探究。结果表明:人工韧带产品结构多样且形态各异,主要与其临床适应症有关;长期植入后材料与骨组织之间的磨损及体内复杂环境下高分子材料的结构变化可能是导致其失效的主要原因,研究可为优化现有人工韧带产品结构、进一步改善其性能提供参考。

关键词: 医用纺织品, 人工韧带, 前交叉韧带, 移出物, 失效机制

Abstract:

In view of large clinical demand for artificial ligament (AL) products and high elimination rate, the present work reports on research where eleven AL products were investigated comprehensively on their geometric features, textures, and surface morphology. In addition, failure mechanisms of a typical product Stryker?-Meadox were explored in terms of mechanical property, fiber morphology and biodegradation through analysis of explants and virgin samples. The results show that the existing AL products have various structures and different shapes, which is related to their clinical indications, and that the surface abrasion of the samples and internal structural changes of the polymers might be the leading causes of the failure after long-term implantation. The findings of this work provide some insights into optimizing the existing AL products.

Key words: medical textile, artificial ligament, anterior cruciate ligament, explant, failure mechanisms

中图分类号: 

  • TS101.4

表1

11种人工韧带移植物的几何特征及组织结构"

试样
编号
宽度/
cm
厚度/
mm
织造
方式
特殊
结构
1# 0.61 0.59 经编 芯壳结构,
芯纱为单丝
2# 0.66 0.87 经编 两端接有末端开有
小孔的塑料管
3# 0.57 0.50 经编 两端接有辅助细线,
细线末尾连接金属丝环
4# 1.77 0.77 机织 一端由细线悬吊,
另一端开有圆孔
5# 4.21 0.40 机织 织带结构
6# 0.44 4.58 经编
机织
经编外壳,
多条机织内芯
7# 0.98 0.76 编织 两端为胶封
8# 0.46 0.47 编织 16股编织结构,
每股中4根编织股纱
9# 0.85 0.56 编织 4股编织结构,
每股中11根编织股纱
10# 1.07 0.67 编织 编织管状结构
11# 0.38 1.60 编织 编织管状结构

表2

1#~3#织造密度测试结果"

试样编号 密度/(线圈·(5 cm)-1)
横密 纵密
1# 24.8 30.2
2# 45.6 105.3
3# 26.2 91.4

表3

4#~6#试样织造密度测试结果"

试样编号 经纬密/(根数·(10 cm)-1)
经密 纬密
4# 39.02 50.24
5# 38.68 51.26
6# 222.87 144.70

表4

7#~11#试样编织密度测试结果"

试样编号 编织角/(°) 编织节点数/(个·cm-1)
7# 42.34 4.12
8# 34.15 14.16
9# 49.32 0.84
10# 24.68 4.40
11# 37.16 6.67

图1

11种纺织基人工韧带织造结构照片"

图2

2种试样体视显微镜照片(×20) "

图3

2种试样的SEM照片(×50)"

图4

6#样品单丝和复丝的红外与热重分析图谱"

图5

原样和移出样的XRD图谱"

图6

原样和移出样芯部的经纱和纬纱典型拉伸断裂曲线"

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