还原氧化石墨烯增强聚乳酸纳米纤维膜的制备及其性能

doi:10.13475/j.fzxb.20210203306

纺织学报 ›› 2021, Vol. 42 ›› Issue (12): 28-33.doi: 10.13475/j.fzxb.20210203306

还原氧化石墨烯增强聚乳酸纳米纤维膜的制备及其性能

王曙东¹^,²^,³(), 董青²^,⁴, 王可¹, 马倩¹

1.盐城工业职业技术学院纺织服装学院, 江苏盐城 224005
2.苏州大学纺织与服装工程学院,江苏苏州 215002
3.江苏金麦穗新能源科技股份有限公司, 江苏盐城 224013
4.苏州工业园区海归人才子女学校, 江苏苏州 215021

收稿日期:2021-02-15 修回日期:2021-09-15 出版日期:2021-12-15 发布日期:2021-12-29
作者简介:王曙东(1983—),男,副教授,博士。主要研究方向为生物医用纤维材料。E-mail: sdwang1983@163.com。
基金资助:
江苏省自然科学基金面上项目(BK20201216);江苏高校青蓝工程培养对象(2018 NO.12);江苏高校青蓝工程培养对象(2019 NO.3);江苏高校自然科学基金面上项目(18KJB540005);江苏高校自然科学基金面上项目(19KJD54000);国家留学基金委资助项目(201908370222)

Preparation and properties of polylactic acid nanofibrous membrane reinforced by reduced graphene oxide

WANG Shudong¹^,²^,³(), DONG Qing²^,⁴, WANG Ke¹, MA Qian¹

1. School of Textile and Clothing, Yancheng Polytechnic College, Yancheng, Jiangsu 224005, China
2. College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215002, China
3. Jiangsu Jinmaisui New Energy Technology Co., Ltd., Yancheng, Jiangsu 224013, China
4. Overseas Chinese Academy of Chiway Suzhou, Suzhou, Jiangsu 215021, China

Received:2021-02-15 Revised:2021-09-15 Published:2021-12-15 Online:2021-12-29

摘要/Abstract

摘要：

针对静电纺聚乳酸(PLA)纳米纤维膜力学强度不高的问题,将一定质量的还原氧化石墨烯(rGO)分散于PLA和二甲基甲酰胺(DMF)纺丝溶液中,通过静电纺丝法制备PLA/rGO复合纳米纤维膜。对纺丝液的流变性能以及复合纳米纤维膜的形貌结构、微观结构和力学性能进行分析,采用四唑盐比色法对复合纳米纤维膜的细胞相容性进行表征。结果表明:rGO成功地复合至PLA纳米纤维中,且以不规则球状形式分布于PLA纳米纤维膜中;rGO的复合显著提升了PLA纳米纤维膜的力学强度,当rGO质量分数为0.6%时,复合纳米纤维膜的断裂强度达2.02 MPa,是纯PLA纳米纤维膜2.3倍;培养1、3和7 d后,小鼠胚胎成骨细胞可在复合纳米纤维膜上生长和增殖,表明PLA/rGO复合纳米纤维膜具有较好的细胞相容性。

关键词: 静电纺丝, 聚乳酸纳米纤维膜, 还原氧化石墨烯, 细胞相容性

Abstract:

To address the low mechanical strength of the electrospinning polylactic acid (PLA) nanofibrous membrane, reduced graphene oxide (rGO) was dispersed into the spinning solution of PLA and dimethylformamide to fabricate PLA/rGO composite nanofibrous membrane by electrospinning. The rheological properties of the spinning solution, structure and mechanical properties of the composite nanofibrous membrane were characterized and analyzed, and the cytocompatibility of the composite nanofibrous membrane was studied by tetrazolium salt colorimetry evaluation. The results show that rGO is successfully blended into the PLA nanofibers by electrospinning, and rGO is distributed in PLA nanofibrous membrane in an irregular spherical form. The mechanical strength of PLA nanofibrous membrane is significantly improved with the blending of rGO. When the mass fraction of rGO was 0.6%, the breaking strength of the composite nanofibrous membrane reached 2.02 MPa, which is 2.3 times higher than that of the pure PLA nanofibrous membrane. After 1, 3 and 7 d culturing, the mouse embryonic osteoblasts displayed growth and proliferation on the composite nanofibrous membrane, which indicates that the PLA/rGO composite nanofibrous membrane offers good cytocompatibility.

Key words: electrospinning, polylactic acid nanofibrous membrane, reduced graphene oxide, cytocompatibility

中图分类号:

TS102.512

王曙东, 董青, 王可, 马倩. 还原氧化石墨烯增强聚乳酸纳米纤维膜的制备及其性能[J]. 纺织学报, 2021, 42(12): 28-33.

WANG Shudong, DONG Qing, WANG Ke, MA Qian. Preparation and properties of polylactic acid nanofibrous membrane reinforced by reduced graphene oxide[J]. Journal of Textile Research, 2021, 42(12): 28-33.

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样品编号	断裂强度/MPa	断裂伸长率/%	弹性模量/MPa
1^#	0.88±0.12	57.53±4.28	1.52±0.21
2^#	1.01±0.19	55.48±3.61	1.84±0.34
3^#	1.43±0.08	48.84±2.85	2.92±0.16
4^#	2.02±0.21	41.39±3.32	4.93±0.51

培养时间/d	支架的吸光度值
培养时间/d	1^#	2^#	3^#	4^#
1	0.091	0.101	0.097	0.115
3	0.136	0.143	0.139	0.225
7	0.197	0.213	0.242	0.304

还原氧化石墨烯增强聚乳酸纳米纤维膜的制备及其性能

Preparation and properties of polylactic acid nanofibrous membrane reinforced by reduced graphene oxide

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