海藻酸盐基非织造医用敷料的研究进展

doi:10.13475/j.fzxb.20241000302

Abstract

Abstract:

Significance With the increasing of the aged population, common diseases such as bedsores and diabetic ulcers are seen more frequently, and market demand for new medical dressings effective in dealing with such problems is increasing. Traditional or single functional medical dressings are difficult to meet the needs of the public. Alginate is widely used for manufacturing medical dressings because of its good biocompatibility, hemostatic and bacteriostatic properties. Nonwoven materials can be processed in a wide range, and the material is soft, breathable and comfortable, suitable for use in medical dressing substrates. Therefore, alginate-based nonwoven medical dressings play an increasingly important role in the treatment of wound bedsores and body surface ulcers.

Progress As a natural polymer polysaccharide, alginate has many carboxylic and hydroxyl groups and is suitable for ion exchange and functional modification. Meanwhile, it has good biocompatibility and degradability, which makes it show great potential in the application field of medical dressing. The nonwoven material has simple preparation process, soft, breathable and comfortable, and is suitable for medical dressing. At present, alginate-based nonwoven dressings can be roughly divided into pure alginate fiber dressings, alginate fiber and other fiber mixed dressings, alginate finishing modified dressings and alginate nanofiber nonwoven dressings. The preparation methods mainly include spinning (electrospinning, microfluidic spinning, centrifugal spinning), carding and strengthening (needling, spunlace), finishing and compound methods. The alginate-based nonwoven dressing has great hemostatic ability, but has insufficient antibacterial ability, which can be modified by alginate derivative or add antibacterial agents to solve the problem in the future. Secondly, the use of diverse nonwoven substrate structures for medical dressings can effectively improve wound healing. Thirdly, materials with specific functions are added to give alginate-based nonwoven medical dressings corresponding functions, expand the application range of medical dressings, and achieve intelligentization of the dressings. The development of multi-functional intelligent dressings (anti-seawater immersion, great water vapor transmission rate, improving immunity, monitoring wound pH value changes, reducing scars, moistening sores, promoting blood coagulation) is an important future development direction. As a new medical dressing, alginate-based nonwoven medical dressing has a favorable development prospect.

Conclusion and Prospect At present, there are many types of alginate-based nonwoven medical dressings associated with various preparation methods. The new multi-functional and integrated alginate-based nonwoven medical dressings are the development direction of medical dressings. In the future, it should actively search for natural antibacterial agents or other new antibacterial agents with wide sources and great non-toxic bacteriostatic performance, or modify alginate to strengthen bacteriostatic performance. The structural design of the innovative alginate-based nonwoven medical dressing achieves the most suitable wound healing environment and maximizes patient convenience. At the same time, by adding specific functional components to medical dressings, the dressings have special functions and realize intelligence on the basis of basic functions, and meet the needs of special wounds.

Key words: medical textile, alginate, nonwoven medical dressing, bacteriostasis, structural design, special function

CLC Number:

TS176.4

WANG Huiting, CHEN Yujian, LIU Shiyi, ZHANG Xiantao, LU Bin, ZOU Zhuanyong, WANG Jian, ZHANG Yinjiang. Research progress in alginate-based nonwoven medical dressings[J].Journal of Textile Research, 2025, 46(06): 240-249.

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URL: http://www.fzxb.org.cn/EN/10.13475/j.fzxb.20241000302

http://www.fzxb.org.cn/EN/Y2025/V46/I06/240

Figures/Tables 3

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