Journal of Textile Research ›› 2020, Vol. 41 ›› Issue (05): 15-19.doi: 10.13475/j.fzxb.20190502306

• Fiber Materials • Previous Articles     Next Articles

Preparation and properties of polyhydroxy fatty acid ester/sodium alginate composite electrospun nanofibers

SUN Fanchen1, GUO Jing1,2, YU Yue1,2, ZHANG Sen1,2   

  1. 1. School of Textile and Material Engineering, Dalian Polytechnic University, Dalian, Liaoning 116034, China
    2. Liaoning Provincial Engineering Research Center of Functional Fiber and Its Composite Materials, Dalian, Liaoning 116034, China
  • Received:2019-05-13 Revised:2020-02-08 Online:2020-05-15 Published:2020-06-02

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Abstract:

Aiming at the problem that polyhydroxy fatty acid ester (P(3HB-co-4HB)) and sodium alginate (SA) are difficult to co-solve under normal circumstances, a P(3HB-co-4HB)/SA nanofiber membrane were prepared using P(3HB-co-4HB) as raw material, SA as modifier, chloroform/water as solvent, alkyl glycoside as emulsifier. The intermolecular forces, thermal properties and morphology of P(3HB-co-4HB)/SA electrospinning nanofibers were characterized by infrared spectrometer, differential scanning calorimeter, and scanning electron microscope. The biocompatibility of P(3HB-co-4HB)/SA nanofibers was characterized by cytotoxicity test and cell co-culture. The results show that the formation of the P(3HB-co-4HB)/SA composite material caused changes in glass transition temperature. When the mass fraction of SA is 6%, the electrospinning nanofibers have a uniform morphology, and the average diameter of the nanofibers is 500 nm. It demonstrates a porosity of 74% and the grade 0 cytotoxicity, and the P(3HB-co-4HB))and SA has good biocompatibility.

Key words: polyhydroxy fatty acid ester, sodium alginate, nanofiber, biocompatibility, electrospinning

CLC Number: 

  • TB332

Fig.1

Experimental process and analysis of co-dissolution mechanism"

Fig.2

Infrared spectrum of SA,P(3HB-co-4HB) and P(3HB-co-4HB)/SA composites"

Fig.3

Schematic diagram of hydrogen bonding"

Fig.4

DSC curves of P (3HB-co-4HB) and P(3HB-co-4HB)/ SA"

Fig.5

SEM images of fiber membrane with different SA mass fractions(×5 000)"

Tab.1

Average diameter and porosity of fiber membrane with different SA mass fractions"

SA质量分数/% 平均直径/μm 孔隙率/%
2
4
6
8
10
12		 0.47±0.02
0.49±0.02
0.50±0.01
0.52±0.03
0.37±0.11
0.42±0.20		 77.0±0.14
75.8±0.09
74.0±0.07
70.5±0.12
89.0±0.23
82.0±0.21

Tab.2

Optical density values of fiber membrane with different SA mass fractions"

时间/h 空白样 不同SA质量分数时的吸光度
0% 2% 4% 6% 8% 10% 12%
12
24
36
48
72
96		 0.302±0.102
0.412±0.109
0.789±0.193
1.293±0.170
1.621±0.142
2.060±0.175		 0.300±0.102
0.403±0.111
0.769±0.122
1.300±0.155
1.600±0.124
2.011±0.155		 0.323±0.139
0.436±0.147
0.796±0.183
1.329±0.170
1.659±0.187
2.075±0.037		 0.339±0.050
0.439±0.138
1.028±0.114
1.408±0.164
1.768±0.061
2.374±0.166		 0.312±0.041
0.439±0.124
0.875±0.138
1.399±0.095
1.768±0.190
2.301±0.108		 0.321±0.036
0.476±0.097
0.888±0.199
1.395±0.181
1.649±0.125
2.210±0.187		 0.327±0.074
0.429±0.079
0.800±0.145
1.410±0.181
1.764±0.100
2.367±0.160		 0.347±0.056
0.450±0.151
0.875±0.136
1.391±0.168
1.835±0.112
2.369±0.109

Fig.6

SEM images of vitro cell culture of fiber membrane with different SA mass fractions(×500)"

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